RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-96
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR; In Situ Hybridization For miR-96 etc.
Target
FOXO3A
Pathway
NA
PubMed ID
Title
MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix
Year
2014
Function
"When IPF fibroblasts interact with collagen-rich matrix, pathologically increased miR-96 expression inhibits FoxO3a function, causing IPF fibroblasts to maintain their pathological phenotype, which may contribute to the progression of IPF."